Tissue Engineering of a Human 3D in vitro Tumor Test System

@inproceedings{Moll2013TissueEO,
  title={Tissue Engineering of a Human 3D in vitro Tumor Test System},
  author={Corinna Moll and Jenny W Reboredo and Thomas V. Schwarz and Antje Appelt and Sebastian Schuerlein and H. Walles and Sarah L. Nietzer},
  booktitle={Journal of visualized experiments : JoVE},
  year={2013}
}
Cancer is one of the leading causes of death worldwide. Current therapeutic strategies are predominantly developed in 2D culture systems, which inadequately reflect physiological conditions in vivo. Biological 3D matrices provide cells an environment in which cells can self-organize, allowing the study of tissue organization and cell differentiation. Such scaffolds can be seeded with a mixture of different cell types to study direct 3D cell-cell-interactions. To mimic the 3D complexity of… CONTINUE READING

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