Tissue Doppler imaging predicts left ventricular dysfunction and mortality in a murine model of cardiac injury.

@article{Neilan2006TissueDI,
  title={Tissue Doppler imaging predicts left ventricular dysfunction and mortality in a murine model of cardiac injury.},
  author={Tomas G. Neilan and Davinder S Jassal and T. Perez-Sanz and Michael J. Raher and Aruna Das Pradhan and Emmanuel S Buys and Fumito Ichinose and David B. Bayne and Elkan F. Halpern and Arthur E. Weyman and Genevi{\`e}ve Anne Derumeaux and Kenneth D. Bloch and Michael H Picard and Marielle Scherrer-Crosbie},
  journal={European heart journal},
  year={2006},
  volume={27 15},
  pages={
          1868-75
        }
}
AIMS Currently available non-invasive imaging methods frequently fail to detect alterations in left ventricular (LV) function despite histological evidence of injury. Tissue Doppler imaging (TDI) can detect subtle LV dysfunction. The aim of this study was to investigate whether TDI indices can predict LV systolic dysfunction and mortality following exposure to doxorubicin (DOX) in mice. METHODS AND RESULTS TDI-derived peak endocardial systolic velocity (V(ENDO)) and strain rate (SR), as well… CONTINUE READING
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