Tissue Doppler imaging detects early asymptomatic myocardial abnormalities in a dog model of Duchenne's cardiomyopathy.

@article{Chetboul2004TissueDI,
  title={Tissue Doppler imaging detects early asymptomatic myocardial abnormalities in a dog model of Duchenne's cardiomyopathy.},
  author={Val{\'e}rie Chetboul and Catherine Escriou and Dominique Tessier and Vincent Richard and J Pouchelon and H{\'e}l{\`e}ne Thibault and Françoise Lallemand and Christian Thuillez and St{\'e}phane Blot and Genevi{\`e}ve Anne Derumeaux},
  journal={European heart journal},
  year={2004},
  volume={25 21},
  pages={
          1934-9
        }
}
AIMS Early diagnosis of Duchenne's dilated cardiomyopathy remains a challenge for conventional echocardiography. We sought to determine whether tissue Doppler imaging (TDI) could detect early alteration in myocardial function in a dog model of Duchenne muscular dystrophy, i.e. the Golden Retriever Muscular Dystrophy (GRMD). METHODS AND RESULTS Myocardial function was assessed by TDI in 20 dogs with normal conventional parameters of systolic function (eight controls and 12 GRMD, 25+/-11 weeks… CONTINUE READING

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