Tissue B-6 vitamer concentrations in rats fed excess vitamin B-6.

@article{Schaeffer1995TissueBV,
  title={Tissue B-6 vitamer concentrations in rats fed excess vitamin B-6.},
  author={Monica C. Schaeffer and Denise Gretz and J. Dennis Mahuren and Stephen P. Coburn},
  journal={The Journal of nutrition},
  year={1995},
  volume={125 9},
  pages={2370-8}
}
Diets containing 1, 10, 100, 175 or 250 times the NRC recommended level of pyridoxine HCl (7 mg/kg) were fed to rats (218 g, 12 per group) to evaluate the effects on tissue B-6 vitamer concentrations. After 10 wk, food intake and body weights did not differ among groups. Overt toxicity was not observed. Tissues were taken from five rats of each group after overnight food deprivation (unfed rats); the remaining seven rats in each group were allowed access to food (fed rats). In plasma of unfed… CONTINUE READING