Tissue‐Specific Responses of Lipoprotein Lipase to Dietary Macronutrient Composition as a Predictor of Weight Gain Over 4 Years

@article{Ferland2012TissueSpecificRO,
  title={Tissue‐Specific Responses of Lipoprotein Lipase to Dietary Macronutrient Composition as a Predictor of Weight Gain Over 4 Years},
  author={Annie Ferland and Marie‐Ludivine Chateau‐Degat and Teri L. Hernandez and Robert H. Eckel},
  journal={Obesity},
  year={2012},
  volume={20}
}
This study evaluated if the effect of dietary macronutrient composition on adipose tissue lipoprotein lipase (ATLPL) and skeletal muscle lipoprotein lipase (SMLPL) predicted the long‐term (over 4 years) changes in body weight and composition in free‐living adults. Using a crossover design, 39 healthy subjects (n = 24 normal weight, n = 7 overweight, n = 8 obese) each followed a 2‐week isocaloric high‐carbohydrate (HC; 55% CHO:25% fat) and high‐fat (HF; 30% CHO:50% fat) diet. On day 15 of each… 
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