Tipifarnib (Janssen Pharmaceutica).

  • Peter Norman
  • Published 2002 in Current opinion in investigational drugs


Janssen is developing tipifarnib (formerly known as R-1 15777), an inhibitor of RAS farnesylation, for the potential treatment of neoplasia [287030], [289610]. Janssen commenced clinical trials in the US, in conjunction with the National Cancer Institute, in April 1997 [287030], [289610], and by May 1999, phase II trials in patients with advanced non-small… (More)


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