Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease.

BACKGROUND Patients with mild or moderate chronic obstructive pulmonary disease (COPD) rarely receive medications, because they have few symptoms. We hypothesized that long-term use of tiotropium would improve lung function and ameliorate the decline in lung function in patients with mild or moderate COPD. METHODS In a multicenter, randomized, double… CONTINUE READING