Tiotropium Attenuates Refractory Cough and Capsaicin Cough Reflex Sensitivity in Patients with Asthma.
@article{Fukumitsu2018TiotropiumAR, title={Tiotropium Attenuates Refractory Cough and Capsaicin Cough Reflex Sensitivity in Patients with Asthma.}, author={Kensuke Fukumitsu and Yoshihiro Kanemitsu and Takamitsu Asano and Norihisa Takeda and Hiroya Ichikawa and Jennifer Maries Go Yap and Satoshi Fukuda and Takehiro Uemura and Osamu Takakuwa and Hirotsugu Ohkubo and Ken Maeno and Yutaka Ito and Tetsuya Oguri and Atsushi Nakamura and Masaya Takemura and Akio Niimi}, journal={The journal of allergy and clinical immunology. In practice}, year={2018}, volume={6 5}, pages={ 1613-1620.e2 } }
33 Citations
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Methodological consideration and selection are necessary for the reasonable assessment of cough sensitivity while employing cough challenges in clinical trials and some factors influencing on the accuracy of outcomes in the experimentally induced cough are detailed.
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The rationale and evidence for the need of long-term treatment for CVA and EBNA, and the development of airway remodeling due to mechanical stress to the airways exerted by long-standing coughing will be discussed.
Comparative effects of capsaicin in chronic obstructive pulmonary disease and asthma (Review)
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A comparative perspective is outlined on the effects of capsaicin and its receptor in the pathophysiology of COPD and asthma, underlying the complex entanglement of molecular signals that bridge the alteration of cellular function with the multitude of clinical effects.
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The role of ATP in cough hypersensitivity syndrome: new targets for treatment
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The generation, release, and regulation of ATP during airway inflammation and its role in the etiology of cough hypersensitivity syndrome are reviewed, including the potential underlying mechanism.
Intermittent Tiotropium Bromide for Episodic Wheezing: A Randomized Trial.
- MedicinePediatrics
- 2022
Intermittent tiotropium bromide treatment may be an effective alternative to current therapies for episodic wheezing and further research on safety and efficacy is indicated.
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