Tiotropium + olodaterol shows clinically meaningful improvements in quality of life.

@article{Singh2015TiotropiumO,
  title={Tiotropium + olodaterol shows clinically meaningful improvements in quality of life.},
  author={Dave Singh and Gary Thomas Ferguson and Josef Bolitschek and Lars Groenke and Christoph Hallmann and Nathan Bennett and Roger Abrahams and Olaf Schmidt and Leif Bjermer},
  journal={Respiratory medicine},
  year={2015},
  volume={109 10},
  pages={1312-9}
}
BACKGROUND Tiotropium + olodaterol improves lung function and symptoms compared to monotherapies in chronic obstructive pulmonary disease (COPD). The OTEMTO 1 and 2 studies investigated the effects of tiotropium + olodaterol on lung function and health-related quality of life compared to placebo in patients with moderate to severe COPD. METHODS In these two replicate, double-blind, parallel-group, placebo-controlled trials, patients were randomised to receive tiotropium + olodaterol 5/5 μg, 2… CONTINUE READING
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