Tinzaparin and other low-molecular-weight heparins: what is the evidence for differential dependence on renal clearance?

Abstract

Since low-molecular-weight heparins (LMWHs) are eliminated preferentially via the kidneys, the potential for accumulation of these agents (and an increased risk of bleeding) is of particular concern in populations with a high prevalence of renal impairment, such as the elderly and patients with cancer. The risk of clinically relevant accumulation of… (More)
DOI: 10.1186/2162-3619-2-21

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