Tinospora cordifolia induces enzymes of carcinogen/drug metabolism and antioxidant system, and inhibits lipid peroxidation in mice.

@article{Singh2006TinosporaCI,
  title={Tinospora cordifolia induces enzymes of carcinogen/drug metabolism and antioxidant system, and inhibits lipid peroxidation in mice.},
  author={Rana P Singh and Subhashish Banerjee and Prikala V Kumar and K. A. Raveesha and Agra Ramesha Rao},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2006},
  volume={13 1-2},
  pages={74-84}
}
The present study is an effort to identify a potent chemopreventive agent against various diseases (including cancer) in which oxidative stress plays an important causative role. Here, we investigated the effect of a hydroalcoholic (80% ethanol: 20% distilled water) extract of aerial roots of Tinospora cordifolia (50 and 100mg/kg body wt./day for 2 weeks) on carcinogen/drug metabolizing phase-I and phase-II enzymes, antioxidant enzymes, glutathione (GSH) content, lactate dehydrogenase and lipid… CONTINUE READING

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