Tinman regulates the transcription of the beta3 tubulin gene (betaTub60D) in the dorsal vessel of Drosophila.

@article{Kremser1999TinmanRT,
  title={Tinman regulates the transcription of the beta3 tubulin gene (betaTub60D) in the dorsal vessel of Drosophila.},
  author={T. Kremser and Kathleen M. Gajewski and Robert A Schulz and Renate Renkawitz-Pohl},
  journal={Developmental biology},
  year={1999},
  volume={216 1},
  pages={327-39}
}
During Drosophila embryogenesis, the beta3 tubulin gene is expressed in the visceral and somatic mesoderm as well as in the dorsal vessel. Transcription of the gene is limited to four pairs of cardioblasts per segment. Here we show that its expression in the dorsal vessel (dv) is mediated by a 333-bp enhancer located upstream of the gene. The homeodomain protein Tinman is also expressed in these cardioblasts, implying that Tinman might be a key regulator of the beta3 tubulin gene. Gel… CONTINUE READING

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