Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction.

@article{1981TimololinducedRI,
  title={Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction.},
  author={},
  journal={The New England journal of medicine},
  year={1981},
  volume={304 14},
  pages={801-7}
}
  • Published 1981 in The New England journal of medicine
A multicenter double-blind randomized study was carried out to compare the effect of timolol (10 mg twice daily) with that of placebo in patients surviving acute myocardial infarction. Treatment was started seven to 28 days after infarction in 1884 patients (945 taking timolol, and 939 placebo), who represented 52 per cent of those evaluated for entry; the patients were followed for 12 to 33 months (mean, 17). There were 152 deaths in the placebo group and 98 in the timolol group. When deaths… CONTINUE READING

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