Timing the origin of human malarias: the lemur puzzle

  title={Timing the origin of human malarias: the lemur puzzle},
  author={M. Pacheco and F. Battistuzzi and R. Junge and O. Cornejo and C. Williams and I. Landau and Lydia Rabetafika and G. Snounou and L. Jones-Engel and A. Escalante},
  journal={BMC Evolutionary Biology},
  pages={299 - 299}
  • M. Pacheco, F. Battistuzzi, +7 authors A. Escalante
  • Published 2011
  • Biology, Medicine
  • BMC Evolutionary Biology
  • BackgroundTiming the origin of human malarias has been a focus of great interest. Previous studies on the mitochondrial genome concluded that Plasmodium in primates, including those parasitic to humans, radiated relatively recently during a process where host switches were common. Those investigations, however, assumed constant rate of evolution and tightly bound (fixed) calibration points based on host fossils or host distribution. We investigate the effect of such assumptions using different… CONTINUE READING
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