Timing of sentinel lymph node biopsy in breast cancer patients receiving neoadjuvant chemotherapy.

The excellent review of the timing of SLNB (before or after neo-adjuvant chemotherapy [NACT]) by Fontein and colleagues suggests that ‘current adjuvant treatment incorporates breast and axillary irradiation to further reduce the probability of axillary recurrences’. Two of the very first studies of locoregional therapy conducted by the NSABP are quoted in… (More)