Timing of Adjuvant Radioimmunotherapy after Cytoreductive Surgery in Experimental Peritoneal Carcinomatosis of Colorectal Origin

@article{Aarts2006TimingOA,
  title={Timing of Adjuvant Radioimmunotherapy after Cytoreductive Surgery in Experimental Peritoneal Carcinomatosis of Colorectal Origin},
  author={Frits Aarts and Manuel J. Koppe and Thijs Hendriks and Julli{\"e}tte E. M. van Eerd and PhD Wim J. G. Oyen and Otto C Boerman and PhD Robert P. Bleichrodt},
  journal={Annals of Surgical Oncology},
  year={2006},
  volume={14},
  pages={533-540}
}
Treatment of patients with peritoneal carcinomatosis (PC) of colorectal cancer (CRC) includes cytoreductive surgery (CS) in combination with (hyperthermic) intraperitoneal chemotherapy (HIPEC), resulting in a limited survival benefit with high morbidity and mortality rates. Radioimmunotherapy (RIT) as adjuvant therapy after CS of CRC has been shown to prolong survival in preclinical studies. However, the optimal setting of RIT remains to be determined. PC was induced by intraperitoneal… CONTINUE READING