Timing and Extent of Surgery in Patients with Familial Medullary Thyroid Carcinoma/Multiple Endocrine Neoplasia 2A-related RET Mutations Not Affecting Codon 634

@article{Gimm2004TimingAE,
  title={Timing and Extent of Surgery in Patients with Familial Medullary Thyroid Carcinoma/Multiple Endocrine Neoplasia 2A-related RET Mutations Not Affecting Codon 634},
  author={O Gimm and J{\"o}rg Ukkat and Barbara E. Niederle and Theresa Weber and Phuong Nguyen Thanh and Michael Brauckhoff and Bruno Niederle and Henning 5 Dralle},
  journal={World Journal of Surgery},
  year={2004},
  volume={28},
  pages={1312-1316}
}
In hereditary medullary thyroid carcinoma (MTC), recommendations regarding timing and extent of surgery are mainly based on the data of patients with the codon 634 RET mutation, which is the most often affected codon. Little is known about whether these recommendations may also be applied to patients with less common RET mutations. We ascertained the data from 140 patients with FMTC/MEN2A-related RET mutation not affecting codon 634 who have been treated at three specialized centers. The… CONTINUE READING

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