Timing Is Everything: Making Neurons versus Glia in the Developing Cortex

@article{Miller2007TimingIE,
  title={Timing Is Everything: Making Neurons versus Glia in the Developing Cortex},
  author={F. D. Miller and Andr{\'e}e S. Gauthier},
  journal={Neuron},
  year={2007},
  volume={54},
  pages={357-369}
}
During development of the mammalian nervous system, neural stem cells generate neurons first and glia second, thereby allowing the initial establishment of neural circuitry, and subsequent matching of glial numbers and position to that circuitry. Here, we have reviewed work addressing the mechanisms underlying this timed cell genesis, with a particular focus on the developing cortex. These studies have defined an intriguing interplay between intrinsic epigenetic status, transcription factors… CONTINUE READING
Highly Influential
This paper has highly influenced 13 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 197 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 115 references

perinatal lethality, hydrocephalus, and agenesis of the corpus callosum

  • B. Deneen, R. Ho, A. Lukaszewicz, C. J. Hochstim, R. M. Gronostajski, D. J. Anderson
  • Proc. Natl. Acad. Sci. USA
  • 2006
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…