Modeling Epigenetic Evolution in a Fluctuating Environment
It is found that in both finite and infinite populations, there is an optimal fraction of offspring with a phenotype different from that of their parents that maximizes a population’s fitness.
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms.
- BiologyAnnual review of genetics
The recently appreciated central role of protein homeostasis in buffering and potentiating genetic variation is reviewed and how these processes mediate the critical influence of the environment on the relationship between genotype and phenotype is discussed.
Phase variation: how to create and coordinate population diversity.
- BiologyCurrent opinion in microbiology
Facing environmental predictability with different sources of epigenetic variation
- Environmental ScienceEcology and evolution
Assessment of sources of epigenetic changes on clonal fish from predictable (lakes) or unpredictable (intermittent streams) environments revealed contrasting contribution of environmentally induced versus stochastic changes according to their origins, suggesting that plasticity and random processes are complementary strategies.
Environmental change and the evolution of genomes: Transposable elements as translators of phenotypic plasticity into genotypic variability
It is proposed that through TE activation, environmental changes can act as inducers of genetic variability, upon which they also act as selective forces, thus triggering rapid evolutionary processes.
Epigenome dynamics: a quantitative genetics perspective
- BiologyNature Reviews Genetics
It is argued that it is timely to consider novel experimental strategies and analysis models to capture the potentially dynamic interplay between chromatin and DNA sequence factors in complex traits.
Stress, genomes, and evolution
- BiologyCell Stress and Chaperones
Key findings are discussed that suggest a rich set of pathways by which Hsp90 can mediate the influences of the environment on the genome, and which can induce novel epigenetic and genetic changes.
Inheritance of epigenome variants across generations during evolution
- BiologyTransgenerational Epigenetics
Epigenetically facilitated mutational assimilation: epigenetics as a hub within the inclusive evolutionary synthesis
- BiologyBiological Reviews of the Cambridge Philosophical Society
Epicetics appears as a hub by which non‐genetically inherited environmentally induced variation in traits can become genetically encoded over generations, in a form of epigenetically facilitated mutational assimilation.
SHOWING 1-10 OF 86 REFERENCES
Evolving responsively: adaptive mutation
- Biology, PsychologyNature Reviews Genetics
The emerging mechanisms of adaptive genetic change cast evolution, development and heredity into a new perspective, indicating new models for the genetic changes that fuel these processes.
Molecular origins of rapid and continuous morphological evolution
- BiologyProceedings of the National Academy of Sciences of the United States of America
A comparative genomic study of repetitive elements in developmental genes of 92 breeds of dogs finds evidence for selection for divergence at coding repeat loci in the form of both elevated purity and extensive length polymorphism among different breeds.
Evidence for the Adaptive Evolution of Mutation Rates
The adaptive advantage of phenotypic memory in changing environments.
- BiologyPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
It is argued that carry-over effects represent an adaptive mechanism on the ecological timescale that fills the gap between short-term individual adaptations and long-term evolutionary adaptations.
The origin of mutants
Some experiments suggesting that cells may have mechanisms for choosing which mutations will occur are described, and the source of this idea is briefly reviewed.
The Population Genetic Theory of Hidden Variation and Genetic Robustness
This article introduces an approximation to the genetic variance in mutation-selection-drift balance that includes the previously used stochastic Gaussian and house-of-cards approximations as limiting cases and concludes that the release of hidden genetic variation is a generic property of models with epistasis or genotype-environment interaction, regardless of whether the wild-type genotype is canalized or not.
An epigenetic mutation responsible for natural variation in floral symmetry
It is shown that a naturally occurring mutant of Linaria vulgaris carries a defect in Lcyc, a homologue of the cycloidea gene which controls dorsoventral asymmetry in Antirrhinum, indicating that epigenetic mutations may play a more significant role in evolution than has hitherto been suspected.
RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse
This work reports a similar modification of the mouse Kit gene in the progeny of heterozygotes with the null mutant Kittm1Alf (a lacZ insertion), identifying an unexpected mode of epigenetic inheritance associated with the zygotic transfer of RNA molecules.
Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life
In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes and offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today.
Microsatellite Instability Generates Diversity in Brain and Sociobehavioral Traits
It is shown that individual alleles of a repetitive polymorphic microsatellite in the 5′ region of the prairie vole vasopressin 1a receptor (avpr1a) gene modify gene expression in vitro, and this regulatory polymorphism predicts both individual differences in receptor distribution patterns and socio-behavioral traits.