Timely and optimal treatment of patients with STEMI
@article{Lassen2013TimelyAO, title={Timely and optimal treatment of patients with STEMI}, author={Jens F. Lassen and Hans Erik B{\o}tker and Christian Juhl Terkelsen}, journal={Nature Reviews Cardiology}, year={2013}, volume={10}, pages={41-48} }
Fibrinolysis is recommended in European and US guidelines for patients with ST-segment elevation myocardial infarction (STEMI) when a strategy of primary percutaneous coronary intervention (PPCI) is associated with ≥120 min delay from first medical contact (FMC), defined as call to the emergency medical services or self-presentation at hospital. Current evidence indicates that reperfusion therapy should be initiated as soon as possible after FMC. However, fibrinolysis cannot be initiated…
55 Citations
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Multicentre analysis of current ST-elevation myocardial infarction acute care pathways
- MedicineOpen Heart
- 2017
Insight was gained into how Dutch PCI centres try to achieve time targets by comparing their care processes with one another and with the European guideline-recommended process, and numerous differences in processes between PCI centres were identified.
Efficacy and Safety of a Pharmaco-Invasive Strategy With Half-Dose Alteplase Versus Primary Angioplasty in ST-Segment–Elevation Myocardial Infarction: EARLY-MYO Trial (Early Routine Catheterization After Alteplase Fibrinolysis Versus Primary PCI in Acute ST-Segment–Elevation Myocardial Infarction)
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For patients with STEMI presenting ⩽6 hours after symptom onset and with an expected PCI-related delay, a PhI strategy with half-dose alteplase and timely PCI offers more complete epicardial and myocardial reperfusion when compared with PPCI.
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- MedicineInternational journal of cardiology
- 2013
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- MedicineKardiologia polska
- 2015
Introduction of a 24/7 primary PCI regional service (STEMI network) led to improved accessibility of invasive diagnosis and treatment and increased reperfusion treatment rates, resulting in reduced in-hospital and 1-year mortality among STEMI patients.
Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries.
- MedicineEuropean heart journal
- 2014
Large variations in reperfusion treatment are still present across Europe, and countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusions therapy.
Remote ischaemic conditioning and healthcare system delay in patients with ST-segment elevation myocardial infarction
- MedicineHeart
- 2016
RIC as adjunctive to pPCI attenuated the detrimental effect of healthcare system delay on myocardial salvage in patients with STEMI, suggesting that the cardioprotective effect of RIC increases with the duration of ischaemia.
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- Medicine, Biology
- 2015
It is shown that a register based randomized clinical trial designed to evaluate bivalirudin versus heparin in patients with ACS and PCI is feasible, with a higher degree of enrollment of “real-life” patients than in conventional randomized clinical trials.
IN-HOSPITAL MORTALITY IN ELDERLY (>75 YEARS) PATIENTS UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION (PCI) WITH ACUTE ST ELEVATION MYOCARDIAL INFARCTION AT AFIC-NIHD RAWALPINDI
- Medicine
- 2015
Primary PCI for elderly patients presenting with acute ST segment elevation myocardial infarction is a safe and effective mode of revascularization with high success rate and low mortality.
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