Time-variant conductance of bilayer membranes treated with monazomycin and alamethicin.

  title={Time-variant conductance of bilayer membranes treated with monazomycin and alamethicin.},
  author={Alexander Mauro and R P Nanavati and Evelyne Heyer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={69 12},
Experimental data obtained on bilayer membranes treated with either of two antibiotics, monazomycin or alamethicin, are presented showing the marked difference in the time course of the rise and subsequent decay of the conductance in response to a positive and negative step of potential established by means of a voltage-clamp feedback circuit. The variation of the conductance with time in these model systems qualitatively mimics the behavior of the "potassium conductance" of squid giant axons… CONTINUE READING

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