Time trends of gastroesophageal reflux disease: a systematic review.

@article{ElSerag2007TimeTO,
  title={Time trends of gastroesophageal reflux disease: a systematic review.},
  author={Hashem B. El-Serag},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2007},
  volume={5 1},
  pages={17-26}
}
There is a perception that the prevalence of gastroesophageal reflux disease (GERD) is increasing, but few studies have directly tackled this issue. By using a systematic approach, this review aimed to assess objectively whether the prevalence of GERD is changing with time. First, population-based studies that reported the prevalence of at least weekly heartburn and/or acid regurgitation were subjected to a time-trend analysis with a Poisson regression model. Second, population-based studies… CONTINUE READING

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