Time to target uric acid to retard CKD progression

@article{Kumagai2016TimeTT,
  title={Time to target uric acid to retard CKD progression},
  author={Takanori Kumagai and Tatsuru Ota and Yoshifuru Tamura and Wen Xiu Chang and Shigeru Shibata and Shunya Uchida},
  journal={Clinical and Experimental Nephrology},
  year={2016},
  volume={21},
  pages={182-192}
}
Uric acid (UA) remains a possible risk factor of chronic kidney disease (CKD) but its potential role should be elucidated given a fact that multidisciplinary treatments assure a sole strategy to inhibit the progression to end-stage renal disease (ESRD). In clinical setting, most observational studies showed that elevation of serum uric acid (SUA) independently predicts the incidence and the development of CKD. The meta-analysis showed that SUA-lowering therapy with allopurinol may retard the… CONTINUE READING
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