Time to recovery of the hypothalamic-pituitary-adrenal axis after curative resection of adrenal tumors in patients with Cushing's syndrome.

@article{Doherty1990TimeTR,
  title={Time to recovery of the hypothalamic-pituitary-adrenal axis after curative resection of adrenal tumors in patients with Cushing's syndrome.},
  author={Gerard M. Doherty and Lynnette K Nieman and Gordon B. Cutler and George P. Chrousos and Jeffrey A. Norton},
  journal={Surgery},
  year={1990},
  volume={108 6},
  pages={1085-90}
}
The recovery time of the hypothalamic-pituitary-adrenal (HPA) axis after curative resection of adrenal tumors in patients with Cushing's syndrome is poorly documented. Eight consecutive patients were treated with a standardized hydrocortisone replacement strategy after curative resection of a cortisol-secreting tumor and the time to recovery of the HPA axis was determined. Hypercortisolism was documented by elevated 24-hour urinary free cortisol levels. Cure was documented by undetectable… CONTINUE READING