Time to reconsider nonsurgical therapy of benign non-toxic multinodular goitre: focus on recombinant human TSH augmented radioiodine therapy.

@article{Fast2009TimeTR,
  title={Time to reconsider nonsurgical therapy of benign non-toxic multinodular goitre: focus on recombinant human TSH augmented radioiodine therapy.},
  author={S{\o}ren Fast and Viveque Egsgaard Nielsen and Steen Joop Bonnema and Laszlo Heged{\"u}s},
  journal={European journal of endocrinology},
  year={2009},
  volume={160 4},
  pages={
          517-28
        }
}
The treatment of benign multinodular goitre (MNG) is controversial, but surgery is recommended in large compressive goitres. While some patients decline surgery others may have contraindications due to comorbidity, since MNG is prevalent in the elderly. Therefore, non-surgical treatment alternatives are needed. Until recently, levothyroxine therapy was the preferred non-surgical alternative, but due to low efficacy and potential side-effects, it is not recommended for routine use in recent… CONTINUE READING

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