Time to pregnancy and exposure to pesticides in Danish farmers. ASCLEPIOS Study Group.

@article{Larsen1998TimeTP,
  title={Time to pregnancy and exposure to pesticides in Danish farmers. ASCLEPIOS Study Group.},
  author={S. B. Larsen and Michael Joffe and Jens Peter Ellekilde Bonde},
  journal={Occupational and Environmental Medicine},
  year={1998},
  volume={55},
  pages={278 - 283}
}
OBJECTIVE: Circumstantial evidence suggests that organic farmers may have higher sperm count than other men, but comprehensive epidemiological studies of male fecundity among farmers have never been carried out. A substantial increase of sperm count is expected to translate into a shorter time to pregnancy--the number of menstrual cycles or months it takes a couple to get pregnant from discontinuation of birth control. Toxicological effects on spermatogenesis in humans and animals have been… Expand
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TLDR
Investigation of the semen quality among farmers exposed to pesticides finds that total functional sperm concentration (TFSC) of sperm was better with group I than group II (p 0.05) and Sperm Motility Index (SMI) score is better in group I more than groupII (p0.05). Expand
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TLDR
This study may offer some evidence for the hypothesis of adverse effects of pesticide exposure on time to pregnancy, but more research is needed to elucidate these effects. Expand
Regional Differences in Time to Pregnancy Among Fertile Women from Five Colombian Regions with Different use of Glyphosate
TLDR
There were differences in TTP between regions, and the observed ecological differences remain unexplained and may be produced by varying exposures to environmental factors, history of contraceptive programs in the region, or psychological distress. Expand
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TLDR
The findings of the study provide limited support for the hypothesis that exposure to pesticides is associated with reduced fertility and can serve as a basis for a hypothesis for future studies. Expand
The impact of pesticides on male fertility
TLDR
The conclusion can be drawn that pesticide exposure may affect spermatogenesis leading to poor semen quality and reduced male fertility. Expand
Time to first pregnancy among women working in agricultural production
TLDR
Work in flower production, irregular relationship, illness and tobacco exposure would be associated with impaired fecundability among women working in cut flowers production. Expand
DDT Exposure, Work in Agriculture, and Time to Pregnancy Among Farmworkers in California
TLDR
Exposure to pesticides, including dichlorodiphenyltrichloroethane (DDT), was associated with longer time to pregnancy (TTP) among women, but not men, reporting exposure to agricultural and home pesticides. Expand
Occupational exposure to chemical substances and time to pregnancy: a systematic review.
TLDR
Despite some uncertainties in the evidence base, it may still be prudent to advise against lead and pesticide exposure at the workplace for couples trying to conceive, as strong indications for adverse effects on TTP were present. Expand
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References

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Findings indicate that an adverse effect of exposure to pesticides on fecundability is likely in a population of fruit growers. Expand
Time to pregnancy: a measure of reproductive function in either sex. Asclepios Project.
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INTRODUCTION: Growing evidence of reproductive effects associated with occupational and environmental agents has created the need for research with sensitive and well validated methods. There is aExpand
Sperm shape abnormalities in carbaryl-exposed employees
TLDR
The findings suggest the need for further study since other workplace-related factor(s) may be responsible for the elevated sperm abnormalities seen in this study, and a definitive link between carbaryl exposure and human seminal defects cannot be established. Expand
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TLDR
To evaluate problems with collecting data on time to pregnancy, telephone interviews were conducted with nearly 700 pregnant women who reported having planned their pregnancies and power curves indicate that relatively small sample sizes are sufficient for investigating an exposure. Expand
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TLDR
Under workplace conditions, 1,2-dibromo-3-chloropropane appears to have a selective effect on the seminiferous tubules under workplace conditions. Expand
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TLDR
It is suggested that EDB may increase the risk of reproductive impairment in workers at exposure levels near the National Institute for Occupational Safety and Health recommended limit of 45 ppb and far below the current standard of the Occupational safety and Health Administration of 20 ppm. Expand
INFERTILITY IN MALE PESTICIDE WORKERS
A number of cases of infertility were discovered among men working in a California pesticide factory. The suspected cause was exposure to the chemical 1,2-dibromo-3-chloropropane (D.B.C.P.). TheExpand
Selection Bias Associated with Contraceptive Practice in Time‐to‐Pregnancy Studies
TLDR
In studies of subfertility using data on time to pregnancy, many pregnancies are not included in analyses because time-to-pregnancy data cannot always be collected, and the more fecund couples are more likely to have birth control failures, the more likely they are to be excluded from analyses. Expand
Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D).
TLDR
Over time, asthenospermia and necrospermia diminished but the abnormal spermatozoa (teratospermia) continued. Expand
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TLDR
Age and subfertility were found to be rather strong determinants of participation in Danish occupational sperm studies and the effect of infertility was modified by occupational exposure status, thus resulting in a tendency to differential selection and possibly biased risk estimates. Expand
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