Time to give up on a single explanation for autism

@article{Happ2006TimeTG,
  title={Time to give up on a single explanation for autism},
  author={F. Happ{\'e} and A. Ronald and R. Plomin},
  journal={Nature Neuroscience},
  year={2006},
  volume={9},
  pages={1218-1220}
}
We argue that there will be no single (genetic or cognitive) cause for the diverse symptoms defining autism. We present recent evidence of behavioral fractionation of social impairment, communication difficulties and rigid and repetitive behaviors. Twin data suggest largely nonoverlapping genes acting on each of these traits. At the cognitive level, too, attempts at a single explanation for the symptoms of autism have failed. Implications for research and treatment are discussed. 
862 Citations

Paper Mentions

Observational Clinical Trial
The purpose of this study is to continue to evaluate the long-term effectiveness of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) in children with Autism Spectrum Disorder (ASD). No… Expand
ConditionsAutistic Disorder
InterventionOther
Observational Clinical Trial
The purpose of this study is to evaluate the safety and efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on subjects with Autism Spectrum Disorder (ASD).  
ConditionsAutistic Disorder
InterventionOther
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