Time-resolved NIR spectroscopy for quantitative analysis of intact pharmaceutical tablets.

@article{Abrahamsson2005TimeresolvedNS,
  title={Time-resolved NIR spectroscopy for quantitative analysis of intact pharmaceutical tablets.},
  author={Christoffer K Abrahamsson and Jonas Johansson and Stefan Andersson-Engels and Sune Svanberg and Staffan Folestad},
  journal={Analytical chemistry},
  year={2005},
  volume={77 4},
  pages={
          1055-9
        }
}
Near-infrared (NIR) spectroscopy is a useful technique for quantitative measurements of intact tablets, but it suffers from limitations due to the fact that changes in the physical properties of a sample strongly affect the recorded spectrum. In this work, time-resolved transmission NIR spectroscopy was utilized to conduct quantitative measurements of intact tablets. The technique enables separation of the absorption properties of the sample from the scattering properties and can therefore… CONTINUE READING

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