Time-related changes in the ultrastructure of osteoclasts after injection of parathyroid hormone in young rats

@article{Holtrop1979TimerelatedCI,
  title={Time-related changes in the ultrastructure of osteoclasts after injection of parathyroid hormone in young rats},
  author={M. Holtrop and Gregory Joseph King and Karen A. Cox and Barry Reit},
  journal={Calcified Tissue International},
  year={1979},
  volume={27},
  pages={129-135}
}
The effects of parathyroid hormone (PTH) on the size of the osteoclasts, nuclei, ruffled borders, and clear zones in long bones of thyroparathyroidectomized (TPTX) rats were quantitated as a function of time. These data were compared with the number of osteoclasts in the bone and with plasma calcium levels. A significant increase in the average size of the ruffled borders was demonstrated 30 min after injection of 50 U of purified bovine PTH, and of the clear zones 30–90 min after PTH. This was… CONTINUE READING
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The relation of ultrastructural changes in osteoclasts to resorption in bone cultures stimulated with parathyroid hormone

  • G. J. King, M. E. Holtrop, L. G. Raisz
  • Metab . Bone Dis . Rel . Res .
  • 1978

The relation of ultrastructural changes in osteoclasts to resorption in bone cultures stimulated with parathyroid hormone, Metab

  • G. J. King, M. E. Holtrop, L. G. Raisz
  • Bone Dis. Rel. Res
  • 1978
2 Excerpts

Quantitation of the ultrastructure of the osteoclast for the evaluation of cell function

  • M. E. Holtrop
  • In P.J. Meunier (ed.): Bone Histomorphometry,
  • 1977
1 Excerpt

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