Time-multiplexed structured illumination using a DMD for optical diffraction tomography.
@article{Lee2017TimemultiplexedSI, title={Time-multiplexed structured illumination using a DMD for optical diffraction tomography.}, author={KyeoReh Lee and Kyoohyun Kim and Geon Kim and Seungwoo Shin and Yongkeun Park}, journal={Optics letters}, year={2017}, volume={42 5}, pages={ 999-1002 } }
We present a time-multiplexing structured illumination control technique for optical diffraction tomography (ODT). Instead of tilting the angle of illumination, time-multiplexed sinusoidal illumination is exploited using a digital micromirror device (DMD). The present method effectively eliminates unwanted diffracted beams from binary DMD patterns, which deteriorates the image quality of the ODT in the previous binary Lee hologram method. We experimentally show the feasibility and advantage of…
99 Citations
Dynamic spatial filtering using a digital micromirror device for high-speed optical diffraction tomography.
- PhysicsOptics express
- 2018
A novel spatial filtering method, based on a second DMD, to dynamically remove the diffraction noise and is able to successfully obtain interferograms at over 1 kHz speed, which is critical for potential high-throughput label-free 3D image cytometry applications.
Partially coherent illumination engineering for enhanced refractive index tomography.
- PhysicsOptics letters
- 2018
It is experimentally demonstrated that a proper design of the PC illumination, different from the familiar bright-field one, and the use of more realistic optical transfer functions (OTFs) have crucial importance in PC-ODT to significantly increase the accuracy in 3D refractive index reconstruction.
Fast label-free optical diffraction tomography compatible with conventional wide-field microscopes
- PhysicsOptical Metrology
- 2019
Partially coherent optical diffraction tomography (PC-ODT) is a labelfree quantitative 3D imaging technique based on the refractive index contrast. It provides fast non-interferometric speckle…
Low-coherence optical diffraction tomography using a ferroelectric liquid crystal spatial light modulator.
- PhysicsOptics express
- 2020
This work introduces a temporally low-coherence ODT technique using a ferroelectric liquid crystal spatial light modulator (FLC SLM) to reduce coherent noise and ensure the high spatiotemporal resolution.
Adaptive wavefront correction structured illumination holographic tomography
- PhysicsScientific Reports
- 2019
A mechanical movement-free compact scanning architecture for SI-HT systems with AWC, implemented by designing and displaying a series of computer-generated holograms (CGH) composed of blazed grating with phase Fresnel lens on a phase-only spatial light modulator (SLM).
Holographic tomography with object rotation and two-directional off-axis illumination.
- Materials ScienceOptics express
- 2017
The main practical obstacle of hybrid tomography is removed, its high-resolution potential is put into practice and the applied type of illumination brings two major benefits.
Quantitative phase and refractive index imaging of 3D objects via optical transfer function reshaping.
- PhysicsOptics express
- 2022
Deconvolution phase microscopy enables high-contrast visualization of transparent samples through reconstructions of their transmitted phases or refractive indexes. Herein, we propose a method to…
Resolution enhancement of digital holographic microscopy via synthetic aperture: a review
- PhysicsLight: Advanced Manufacturing
- 2022
Digital holographic microscopy (DHM), which combines digital holography with optical microscopy, is a wide field, minimally invasive quantitative phase microscopy (QPM) approach for measuring the 3D…
Pupil-aberration calibration with controlled illumination for quantitative phase imaging.
- PhysicsOptics express
- 2021
The proposed method recovers pupil information by utilizing the cross-spectral density between optical fields at different incident angles and allows both thin and weakly scattering three-dimensional samples for calibration.
Common-path intrinsically achromatic optical diffraction tomography.
- PhysicsBiomedical optics express
- 2021
The results show that the decreased coherence offers much reduced coherent noise and higher fidelity tomographic reconstruction especially when applied nonnegativity constraint regularization procedure.
References
SHOWING 1-10 OF 39 REFERENCES
Active illumination using a digital micromirror device for quantitative phase imaging.
- PhysicsOptics letters
- 2015
A powerful and cost-effective method for active illumination using a digital micromirror device (DMD) for quantitative phase-imaging techniques and the fast and stable illumination-control capability of the proposed method is demonstrated by imaging colloidal spheres and biological cells.
Active limited-angle tomographic phase microscope
- PhysicsJournal of biomedical optics
- 2015
An active, holographic tomography system, working with limited angle of projections, realized by optical-only, diffraction-based beam steering is demonstrated, providing an elegant solution to viewing angle shifting and adding new capabilities of the holographic microscope system.
Diffraction optical tomography using a quantitative phase imaging unit.
- PhysicsOptics letters
- 2014
3-D RI tomograms of nonbiological samples such as polystyrene microspheres, as well as biological samples including human red blood cells and breast cancer cells, are presented.
3D differential phase contrast microscopy
- PhysicsSPIE BiOS
- 2016
3D volume reconstruction can be achieved via a fast inversion method, without the intermediate 2D phase retrieval step, and the transverse resolution achieves twice the NA of coherent systems, while axial resolution is also improved 2× as compared to holographic imaging.
Large-scale optical diffraction tomography for inspection of optical plastic lenses.
- Physics, Materials ScienceOptics letters
- 2016
ODT was used to reconstruct a 3-D RI distribution of the plastic lens with unprecedented RI sensitivity (Δn=4.21×10(-5) and high resolution) and defects in the lens, generated by pulsed laser ablation, were detected using the present method.
Optical diffraction tomography using a digital micromirror device for stable measurements of 4D refractive index tomography of cells
- BiologySPIE BiOS
- 2016
This work systematically study the precision and stability of the ODT system equipped with a DMD and present measurements of 3-D and 4-D RI maps of various types of live cells including human red blood cells, whiteBlood cells, hepatocytes, and HeLa cells.
Cell refractive index tomography by digital holographic microscopy.
- PhysicsOptics letters
- 2006
Digital holographic microscopy is applied to perform optical diffraction tomography of a pollen grain for the first time, with a precision of 0.01 for the refractive index estimation and a spatial resolution in the micrometer range.
Synthetic aperture fourier holographic optical microscopy.
- PhysicsPhysical review letters
- 2006
Synthetic microscopic imaging is demonstrated in which spatial frequencies that are well outside the modulation transfer function of the collection optical system are recorded while maintaining the long working distance and wide field of view.
Single-cell diffraction tomography with optofluidic rotation about a tilted axis
- Physics, MathematicsSPIE NanoScience + Engineering
- 2015
The 3D reconstruction can be improved by taking into account such a tilted rotational axis in the reconstruction process by addressing the problem that arises when the trapped cell is not rotating about an axis perpendicular to the imaging plane, but is instead arbitrarily tilted.
Optical diffraction tomography for high resolution live cell imaging.
- PhysicsOptics express
- 2009
The quantitative refractive index map can potentially serve as an intrinsic assay to provide the molecular concentrations without the addition of exogenous agents and also to provide a method for studying the light scattering properties of single cells.