Time-matched pre- and postsynaptic changes of GABAergic synaptic transmission in the developing mouse superior colliculus.

@article{Kirischuk2005TimematchedPA,
  title={Time-matched pre- and postsynaptic changes of GABAergic synaptic transmission in the developing mouse superior colliculus.},
  author={Sergei Kirischuk and Ren{\'e} J{\"u}ttner and Rosemarie Grantyn},
  journal={The Journal of physiology},
  year={2005},
  volume={563 Pt 3},
  pages={795-807}
}
Developmental changes in the kinetics of GABAergic postsynaptic currents have been reported for various brain structures. However, it has remained unclear whether these modifications are matched by presynaptic changes. We addressed this question by analysing evoked IPSCs (eIPSCs) in mouse superior colliculus slices between postnatal day (P) 1 and 22. eIPSCs were elicited by electrical stimulation and measured in the whole-cell patch-clamp configuration. IPSCs were analysed using the binomial… CONTINUE READING

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