Time for a change

  title={Time for a change},
  author={N. Pace},
  • N. Pace
  • Published 2006
  • Biology, Medicine
  • Nature
Prokaryote: gene-sequence comparisons show the tree of life consists of bacteria, eukarya and archaea. The use of the term ‘prokaryote’ fails to recognize that an idea about life's origins has been proved wrong.It's only wordsOld textbook divisions of the living world into prokaryotes and eukaryotes should be condemned to history, says Norman Pace. Cells were either prokaryotic, with no nuclei or nuclear membranes; or eukaryotic, equipped with a membrane-bounded nucleus. Comparisons of RNA and… Expand
Eukaryotes first: how could that be?
If the canonical three-domain tree in which Archaea and Eukarya are sisters is accepted, EF entails that Bacteria and Archaea are convergently prokaryotic, and it is asked what this means and how it might be tested. Expand
The indefinable term ‘prokaryote’ and the polyphyletic origin of genes
It is concluded that given the absence of truth in common characteristics between archaea and bacteria, the origin of genes of proteins should have been polyphyletic. Expand
Prokaryote/Eukaryote Dichotomy and Bacteria/Archaea/Eukarya Domains: Two Inseparable Concepts
It is concluded that the organizational and functional concept of a prokaryotes/eukaryotes dichotomy can be easily supplemented by the phylogenetic concept Bacteria/Archaea/Eukarya, resulting in a consensual proposal that integrates both phenotypic and genotypic criteria. Expand
The hidden side of the prokaryotic cell: rediscovering the microbial world.
  • R. Guerrero, M. Berlanga
  • Biology, Medicine
  • International microbiology : the official journal of the Spanish Society for Microbiology
  • 2007
Two characteristics of prokaryotic cells that were not known to Stanier and van Niel but which now allow us to understand the basis of many characteristics that are fully developed in eukaryosis cells are discussed. Expand
Two faces of the prokaryote concept.
  • J. Sapp
  • Biology, Medicine
  • International microbiology : the official journal of the Spanish Society for Microbiology
  • 2006
How the two concepts became inseparable; how the prokaryotes came to signify a monophyletic group that preceded the eukaryotes, and how this view remained unquestioned for 15 years, until the birth of molecular evolutionary biology and coherent methods for bacteria phylogenetics based on 16S rRNA is examined. Expand
[Plasmids of archaea as possible ancestors of DNA-containing viruses].
The role of structural proteins coded by pR1S in the process of formation of vesicle membrane complex is paid special attention and can be viewed as possible ancestors of DNA-containing viruses. Expand
Evidence that the root of the tree of life is not within the Archaea.
Using gene insertions and deletions found within protein synthesis factors present in all prokaryotes and eukaryotes, statistically significant evidence that the root of life is outside the Archaea is presented. Expand
Base excision repair in Archaea: back to the future in DNA repair.
The most important proteins involved in base excision repair, namely glycosylase, AP lyases, AP endonucleases, polymerases, sliding clamps, flap endon nucleases, and ligases, will be discussed and compared with bacterial and eukaryotic ones. Expand
Unique Solutions to Universal Problems : Studies of the Archaeal Cell
The research presented in this thesis describes unique features of the archaeal cell and influences the understanding of the entire tree of life. Expand
Eradicating typological thinking in prokaryotic systematics and evolution.
  • W. Doolittle
  • History, Medicine
  • Cold Spring Harbor symposia on quantitative biology
  • 2009
It is argued that "species," "domains," and the "TOL" are reifications that the authors can do without, especially as genomics dissolves into metagenomics. Expand