Time for a Different Approach to Lyme Disease and Long-Term Symptoms.

@article{Melia2016TimeFA,
  title={Time for a Different Approach to Lyme Disease and Long-Term Symptoms.},
  author={M. Melia and P. Auwaerter},
  journal={The New England journal of medicine},
  year={2016},
  volume={374 13},
  pages={
          1277-8
        }
}
The condition of most patients with Lyme disease improves after initial antibiotic therapy; however, 10 to 20% of treated patients may have lingering symptoms of fatigue, musculoskeletal pains, disrupted sleep, and lack of customary mental functions. The plausible idea that additional antimicrobial therapy for potentially persistent bacterial infection would foster improvement has been a touchstone of hope in the 40 years since discovery of the disease in the mid-1970s. Patients with long… Expand

References

SHOWING 1-10 OF 10 REFERENCES
Treatment trials for post-Lyme disease symptoms revisited.
A critical appraisal of "chronic Lyme disease".
Randomized Trial of Longer-Term Therapy for Symptoms Attributed to Lyme Disease.
Long-term assessment of health-related quality of life in patients with culture-confirmed early Lyme disease.
Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease.
Testing patients with non-specific symptoms for antibodies against Borrelia burgdorferi sensu lato does not provide useful clinical information about their aetiology.
  • M. Markowicz, D. Kivaranovic, G. Stanek
  • Medicine
  • Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2015
High frequency of false positive IgM immunoblots for Borrelia burgdorferi in clinical practice.