Time evolution of in vivo articular cartilage repair induced by bone marrow stimulation and scaffold implantation in rabbits.

@article{SanchoTello2015TimeEO,
  title={Time evolution of in vivo articular cartilage repair induced by bone marrow stimulation and scaffold implantation in rabbits.},
  author={M. Sancho-Tello and Francisco Forriol and Pablo Gastaldi and A Ruiz-Sauri and Jos{\'e} Javier Mart{\'i}n de Llano and Edurne Novella-Maestre and Carmen M Antolinos-Turp{\'i}n and Jos{\'e} Antonio G{\'o}mez-Tejedor and Jos{\'e} Luis G{\'o}mez Ribelles and C. Carda},
  journal={The International journal of artificial organs},
  year={2015},
  volume={38 4},
  pages={
          210-23
        }
}
PURPOSE Tissue engineering techniques were used to study cartilage repair over a 12-month period in a rabbit model. METHODS A full-depth chondral defect along with subchondral bone injury were originated in the knee joint, where a biostable porous scaffold was implanted, synthesized of poly(ethyl acrylate-co-hydroxyethyl acrylate) copolymer. Morphological evolution of cartilage repair was studied 1 and 2 weeks, and 1, 3, and 12 months after implantation by histological techniques. The 3-month… CONTINUE READING
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