Time-dependent sensitivity analysis of biological networks: coupled MAPK and PI3K signal transduction pathways.

Abstract

Sensitivity analysis has been widely used in the studies of complicated chemical reaction and biological networks, for example, in combustion studies and metabolic control analysis of pathways. In the latter cases, the responses of system properties at steady states with respect to changes of parameters, such as initial concentrations and rate constants… (More)

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Cite this paper

@article{Hu2006TimedependentSA, title={Time-dependent sensitivity analysis of biological networks: coupled MAPK and PI3K signal transduction pathways.}, author={Dawei Hu and J. C. Yuan}, journal={The journal of physical chemistry. A}, year={2006}, volume={110 16}, pages={5361-70} }