Time-dependent mechanics and measures of glial activation and behavioral sensitivity in a rodent model of radiculopathy.

@article{Rothman2010TimedependentMA,
  title={Time-dependent mechanics and measures of glial activation and behavioral sensitivity in a rodent model of radiculopathy.},
  author={Sarah M. Rothman and Kristen Nicholson and Beth Winkelstein},
  journal={Journal of neurotrauma},
  year={2010},
  volume={27 5},
  pages={803-14}
}
Nerve root compression induces persistent behavioral hypersensitivity and spinal glial reactivity. Viscoelastic properties of neural tissues suggest that physiologic outcomes may depend on the duration of an applied nerve root compression. This study evaluated the time-dependent properties of the root under compression in the context of pain-related behavioral and physiologic outcomes. The decrease in applied load measured by load relaxation under compression was quantified for rat cervical (C6… CONTINUE READING