Time-dependent effects of global cerebral ischemia on anxiety, locomotion, and habituation in rats.

@article{Milot2009TimedependentEO,
  title={Time-dependent effects of global cerebral ischemia on anxiety, locomotion, and habituation in rats.},
  author={Marc R. Milot and H{\'e}l{\`e}ne Plamondon},
  journal={Behavioural brain research},
  year={2009},
  volume={200 1},
  pages={173-80}
}
Although changes in emotionality represent common features of post-ischemic recovery in humans, little is known about the effects of global cerebral ischemia on standard behavioral measures of emotionality in rodents. The present study investigated anxiety, locomotor activity, and habituation in test-naïve ischemic (subjected to 10 min global ischemia) and sham-operated rats tested 1, 5, 15, and 30 days post-reperfusion in the elevated plus-maze and the open-field. Although rats tested on day 1… CONTINUE READING