Time-dependent disruption of passive avoidance acquisition by post-training intra-amygdala injection of tetrodotoxin in rats.


The role of the amygdala (AM) in the consolidation of the passive avoidance reaction (PAR) has been examined with the tetrodotoxin (TTX)-induced functional block of this structure. Rats were trained in the step-through PAR and anesthetized with ketamine. TTX injected immediately after acquisition into both AM (2 x 10 ng) significantly reduced avoidance of… (More)


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