Time-dependent changes in cerebral and cardiovascular parameters in isoflurane-nitrous oxide-anesthetized dogs.

@article{Turner1984TimedependentCI,
  title={Time-dependent changes in cerebral and cardiovascular parameters in isoflurane-nitrous oxide-anesthetized dogs.},
  author={Dorothea. Turner and Neal F. Kassell and Tomoaki Sasaki and Youssef G. Comair and David J. Boarini and D O Beck},
  journal={Neurosurgery},
  year={1984},
  volume={14 2},
  pages={
          135-41
        }
}
The purpose of this study was to examine the time-dependent effects of isoflurane-nitrous oxide anesthesia on cerebral blood flow and metabolism and on cardiovascular parameters. Eleven 15-kg mongrel dogs were anesthetized with 0.8% isoflurane (approximately 1.3 MAC (minimal anesthetic concentration], 70% nitrous oxide, and 30% O2 and were paralyzed with pancuronium. Blood flow (using the radioactive microsphere technique) and cerebrovascular and cardiovascular parameters were measured 6 times… CONTINUE READING
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