Time-dependent, layer-specific modulation of sensory responses mediated by neocortical layer 1.

@article{Shlosberg2006TimedependentLM,
  title={Time-dependent, layer-specific modulation of sensory responses mediated by neocortical layer 1.},
  author={Dan Shlosberg and Yael Amitai and Rony Azouz},
  journal={Journal of neurophysiology},
  year={2006},
  volume={96 6},
  pages={3170-82}
}
An essential component of feedback and top-down information in the cortical column arrives at layer 1 (L1) where it contacts distal dendrites of pyramidal neurons. Although much is known about the anatomical organization of L1 fibers, their contribution to sensory information processing remains to be determined. We assessed the physiological significance of L1 inputs by performing extracellular recordings in vivo from neurons in the primary somatosensory cortex of rodents. We found that… CONTINUE READING
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