Time-dependence of risperidone and asenapine sensitization and associated D2 receptor mechanism.

@article{Gao2013TimedependenceOR,
  title={Time-dependence of risperidone and asenapine sensitization and associated D2 receptor mechanism.},
  author={Jun Gao and Ming Li},
  journal={Behavioural brain research},
  year={2013},
  volume={257},
  pages={286-94}
}
When an antipsychotic drug is given repeatedly and intermittently, there is often a long-term increase in its behavioral efficacy, termed antipsychotic sensitization. With the passage of time, the magnitude of antipsychotic sensitization may increase or decrease based on the principle of time-dependent sensitization (TDS) or memory decay, respectively. In… CONTINUE READING