Time dependence of effect of nitric oxide synthase inhibition on cerebral ischemic damage.

@article{Zhang1995TimeDO,
  title={Time dependence of effect of nitric oxide synthase inhibition on cerebral ischemic damage.},
  author={Feng Zhang and Shujun Xu and C Iadecola},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={1995},
  volume={15 4},
  pages={595-601}
}
Nitric oxide, a potent vasodilator and an inhibitor of platelet aggregation, may be beneficial in the early stages of focal cerebral ischemia as it may facilitate collateral blood flow to the ischemic territory. Accordingly, the effect of inhibition of nitric oxide synthesis on cerebral ischemic damage may vary depending on the timing of the inhibition… CONTINUE READING