Time dependence of cyclic tensile strain on collagen production in tendon fascicles.

@article{Maeda2007TimeDO,
  title={Time dependence of cyclic tensile strain on collagen production in tendon fascicles.},
  author={Eijiro Maeda and Julia C Shelton and Dan L. Bader and David A Lee},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={362 2},
  pages={399-404}
}
Mechanical loading is a regulator of tissue metabolism in tendon, which may lead to alterations in structural and mechanical properties via mechanotransduction processes. The present study investigated specified responses of tenocyte metabolism in isolated tendon fascicles subjected to four loading regimes. Cyclic tensile strain of 3% amplitude superimposed on a 2% static strain was applied to the fascicles for 10min, 1, 6 or 24h of a 24-h incubation period. Collagen synthesis, assessed by [(3… CONTINUE READING

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