Time course of skin photosensitivity following trimethylpsoralen bath PUVA.

@article{Man2000TimeCO,
  title={Time course of skin photosensitivity following trimethylpsoralen bath PUVA.},
  author={Irene Man and Nicholas W. J. Wainwright and N K Gibbs and James Henry Ferguson},
  journal={Photodermatology, photoimmunology & photomedicine},
  year={2000},
  volume={16 5},
  pages={
          211-5
        }
}
One aspect of bath photochemotherapy (PUVA) that requires clarification is the duration of psoralen-induced cutaneous photosensitisation under conditions simulating clinical use. Using a half back comparison study technique, we investigated the persistence of trimethylpsoralen (TMP)-induced photosensitivity in skin irradiated to simulate a first PUVA exposure compared with un-irradiated skin. Baseline UVA minimal erythema dose and minimal phototoxic dose (MPD) were determined in 13 healthy… CONTINUE READING