Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice.

@article{Paoni2002TimeCO,
  title={Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice.},
  author={Nicholas F Paoni and Franklin Peale and Fay Wang and Carol Errett-Baroncini and Hope G Steinmetz and Karen Toy and Wei Bai and P. Mickey Williams and Stuart Bunting and Mary E. Gerritsen and Lyn Powell-Braxton},
  journal={Physiological genomics},
  year={2002},
  volume={11 3},
  pages={263-72}
}
DNA microarrays were used to measure the time course of gene expression during skeletal muscle damage and regeneration in mice following femoral artery ligation (FAL). We found 1,289 known sequences were differentially expressed between the FAL and control groups. Gene expression peaked on day 3, and the functional cluster "inflammation" contained the greatest number of genes. Muscle function was depressed for 3 days postligation, but returned to normal by day 7. Decreased muscle function was… CONTINUE READING
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Time course of arteriogenesis following femoral artery occlusion in the rabbit

  • IE Hoefer, N van Royen, IR Buschmann, JJ Piek, W. Schaper
  • Cardiovasc Res
  • 2001
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