Time course of programmed cell death in Ciona intestinalis in relation to mitotic activity and MAPK signaling.

@article{Tarallo2004TimeCO,
  title={Time course of programmed cell death in Ciona intestinalis in relation to mitotic activity and MAPK signaling.},
  author={Raffaella Tarallo and Paolo Sordino},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2004},
  volume={230 2},
  pages={251-62}
}
Programmed cell death (PCD) in the ascidian species Ciona intestinalis (Tunicata; Chordata) is investigated from early larvae to juvenile stages, by means of digoxigenin-based terminal deoxynucleotidyl transferase-mediated biotinylated UTP nick end labeling (TUNEL) technique. At first, PCD in the swimming larva affects trunk mesenchyme and central nervous system (CNS), then it participates extensively to metamorphosis, until it is restricted to developing organs of juveniles. Analysis of… CONTINUE READING

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