Time course of peritoneal tissue plasminogen activator after experimental colonic surgery: effect of hyaluronan-based antiadhesive agents and bacterial peritonitis.

@article{Reijnen2002TimeCO,
  title={Time course of peritoneal tissue plasminogen activator after experimental colonic surgery: effect of hyaluronan-based antiadhesive agents and bacterial peritonitis.},
  author={Michel M P J Reijnen and Lena Holmdahl and Teake Kooistra and Peter Falk and Th{\"y}s Hendriks and Harry van Goor},
  journal={The British journal of surgery},
  year={2002},
  volume={89 1},
  pages={103-9}
}
BACKGROUND This study assessed the peritoneal fibrinolytic response during the first week after colonic surgery in rats with and without bacterial peritonitis, and possible modulation of the response by two hyaluronan-based antiadhesive agents. METHODS A colonic anastomosis was constructed in 90 male Wistar rats. Peritonitis was induced in another 108 rats and a colonic anastomosis was constructed after 24 h. Rats in both groups were randomized into an untreated group or one of two groups… CONTINUE READING
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