Time course of hepatic gene expression and plasma vitellogenin protein concentrations in estrone-exposed juvenile rainbow trout (Oncorhynchus mykiss).

@article{Osachoff2016TimeCO,
  title={Time course of hepatic gene expression and plasma vitellogenin protein concentrations in estrone-exposed juvenile rainbow trout (Oncorhynchus mykiss).},
  author={Heather Louise Osachoff and Lorraine Lok-Lun Yu Brown and Leena Tirrul and Graham C van Aggelen and Fiona S. L. Brinkman and Christopher Robin Kennedy},
  journal={Comparative biochemistry and physiology. Part D, Genomics & proteomics},
  year={2016},
  volume={19},
  pages={
          112-119
        }
}
Estrone (E1), a natural estrogen hormone found in sewage effluents and surface waters, has known endocrine disrupting effects in fish, thus, it is a contaminant of emerging concern. Juvenile rainbow trout (Oncorhynchus mykiss) were exposed to an environmentally-relevant concentration of E1 (24ng/L E1 [0.1nM]) for 7d and then placed in clean water for a 9d recovery period. RNA sequencing showed transcripts from numerous affected biological processes (e.g. immune, metabolic, apoptosis, clotting… CONTINUE READING
Tweets
This paper has been referenced on Twitter 3 times. VIEW TWEETS