Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID).

@article{Sudduth2017TimecourseOG,
  title={Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID).},
  author={Tiffany L. Sudduth and Erica M. Weekman and Brittani R Price and Jennifer L Gooch and Abigail E. Woolums and Christopher M. Norris and Donna M Wilcock},
  journal={Neuroscience},
  year={2017},
  volume={341},
  pages={
          42-51
        }
}
Vascular cognitive impairment and dementia (VCID) is the second leading cause of dementia behind Alzheimer's disease (AD) and is a frequent co-morbidity with AD. Despite its prevalence, little is known about the molecular mechanisms underlying the cognitive dysfunction resulting from cerebrovascular disease. Astrocytic end-feet almost completely surround intraparenchymal blood vessels in the brain and express a variety of channels and markers indicative of their specialized functions in the… CONTINUE READING