Time course of changes in cocaine self-administration behavior in rats during immunization with the cocaine vaccine IPC-1010

@article{Kantak2001TimeCO,
  title={Time course of changes in cocaine self-administration behavior in rats during immunization with the cocaine vaccine IPC-1010},
  author={Kathleen Kantak and Stephanie L. Collins and Julian Bond and Barbara S. Fox},
  journal={Psychopharmacology},
  year={2001},
  volume={153},
  pages={334-340}
}
Rationale: Following a 6-week immunization period consisting of three biweekly injections of the cocaine vaccine IPC-1010, the reacquisition of cocaine self-administration behavior in rats was previously shown to be reduced in a manner that was dependant on serum antibody level. The present studies were conducted to examine additional issues relevant to the clinical use of the vaccine. Objectives: One experiment was conducted to address the issue of whether exposure to cocaine during the… CONTINUE READING